Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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4,156 – 4,170 of 6,661 results

4,156

Medchemexpress LLC Ssr180711 (hydrochloride) | 446031-79-4 | 99.9% | 361.66 | 100 MG

SSR180711 hydrochloride is an orally active, selective, and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. It acts on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM). This compound increases glutamatergic neurotransmission, ACh release, and long-term potentiation (LTP) in the hippocampus. It is intended for research use only.

Orally active
Selective and reversible α7 n-AChRs partial agonist
Increases glutamatergic neurotransmission, ACh release, and long-term potentiation (LTP) in the hippocampus
Selective for the α7 receptor subtype compared to α4β2, α3β2, α3β4, and α1β1γδ human n-AChR subtypes (IC50>5 μM)
Rapidly penetrates into the brain (ID50=8 mg/kg; p.o.)

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4,157

Medchemexpress LLC EPZ011989 hydrochloride | 2095432-26-9 | 99.4% | 642.27 | 5 MG

EPZ011989 hydrochloride is a potent and orally active Zeste Homolog 2 (EZH2) inhibitor, with a Ki value of <3 nM. It shows anti-tumor activity and is a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Potent and orally active Zeste Homolog 2 (EZH2) inhibitor
Ki value of <3 nM
Shows anti-tumor activity
Click chemistry reagent
Contains an Alkyne group
Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups

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4,158

Medchemexpress LLC Ponatinib (hydrochloride) | 1114544-31-8 | 99.8% | 569.02 | 10 MG

Ponatinib hydrochloride is a hydrochloride of ponatinib, an orally active multi-targeted kinase inhibitor. It targets Abl, PDGFRα, VEGFR2, FGFR1, and Src with various IC50s.

Reduces the viability, migration, and function of human endothelial cells.
Decreased cell viability in HUVEC cells in a dose-dependent manner.
Increased the percentage of annexin/PI labeled cells in HUVEC cells.
Reduced VEGF-induced migration in HUVEC cells.
Protects mice from lethal influenza infection by inhibiting cytokine storm.
Treated mice had higher survival rates and reduced the infiltration of neutrophils.

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4,159

Medchemexpress LLC Ro 41-1049 hydrochloride | 127917-66-2 | MFCD00900596 | 100.0% | 301.77 g·mol⁻¹ | C12H13ClFN3OS | 1 ML

Ro 41-1049 hydrochloride is a reversible, selective monoamine oxidase A (MAO-A) inhibitor supplied for research use. It is available as a solid and as a pre-made 10 mM solution in DMSO (1 mL), and is provided with a high reported purity to support reproducible in vitro experiments.

Reversible, selective MAO-A inhibition suitable for biochemical assays.
Supplied as solid or pre-made 10 mM solution in DMSO (1 mL) for convenience.
High reported purity to reduce confounding impurities.
Characterized by CAS number 127917-66-2 and known molecular weight for accurate dosing.
Intended for research use only; not for human or clinical use.

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4,160

Medchemexpress LLC Zoniporide hydrochloride hydrate | 863406-85-3 | 99.4% | 374.82 g/mol | C17H19ClN6O2 | 25 MG

Zoniporide hydrochloride hydrate is the hydrochloride hydrate salt of zoniporide, a potent and selective inhibitor of the sodium-hydrogen exchanger isoform 1 (NHE-1) used for research applications. It is provided as a high-purity solid suitable for in vitro and ex vivo studies of NHE-1 function and related cardiovascular and platelet biology.

Potent and selective NHE-1 inhibition (human IC50 ~14 nM).
Inhibits ex vivo NHE-1-dependent platelet swelling (IC50 ~59 nM).
High purity (>99% by HPLC).
Available as the hydrochloride hydrate salt for improved handling and stability.
Molecular weight 374.82 g/mol; molecular formula C17H19ClN6O2.
Supplied in small research quantities, e.g., 25 MG.

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4,161

Medchemexpress LLC SGK1-IN-3 hydrochloride | 96.7% | C23H21Cl3N6O3S | 25 MG

SGK1-IN-3 hydrochloride is a potent SGK1 inhibitor with an IC50 of less than 1 μM. It has the potential for the research of osteoarthritis.

Potent SGK1 inhibitor with an IC50 of <1 μM
Potential for osteoarthritis research

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4,162

Medchemexpress LLC SB-612111 hydrochloride | 99.6% | 454.86 | 1 ML

SB-612111 hydrochloride is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist with high affinity for hORL-1 (Ki = 0.33 nM). It demonstrates selectivity for μ-, κ-, and δ-receptors. This compound effectively antagonizes the pronociceptive action of Nociceptin in an acute pain model.

Potent ORL-1 antagonist with high affinity.
Exhibits selectivity for μ-, κ-, and δ-receptors.
Effectively antagonizes pronociceptive action of Nociceptin.
Demonstrates antihyperalgesic effects in animal models.

Pricing & Availability

4,163

Medchemexpress LLC ARG1-IN-1 hydrochloride | 00-00-0 | 90.0% | C11H22BClN2O4 | 10MG

ARG1-IN-1 hydrochloride is a research compound that selectively inhibits human arginase 1, with a reported IC50 of 29 nM. Supplied as the hydrochloride salt, the material is typically offered at 90.0% purity and is intended for biochemical and pharmacological research applications only.

Potent arginase 1 inhibition (IC50 = 29 nM).
Supplied as a hydrochloride salt for chemical stability.
Typical purity 90.0% suitable for research use.
Appropriate for in vitro biochemical and cell-based assays.
Provided in milligram-scale quantities for laboratory studies.

Pricing & Availability

4,164

Medchemexpress LLC Guanabenz hydrochloride | 23113-43-1 | 99.9% | 25 MG

Guanabenz hydrochloride is an orally active α-2-adrenoceptor agonist with antihypertensive and antiparasitic activity. It interferes with ER stress-signalling and has protective effects in cardiac myocytes. It is also used for the research of high blood pressure. For research use only.

Orally active alpha-2-adrenoceptor agonist
Exhibits antihypertensive activity
Displays antiparasitic activity
Interferes with ER stress-signalling
Has protective effects in cardiac myocytes
Used for research of high blood pressure

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4,165

Medchemexpress LLC Alpelisib hydrochloride | 1584128-91-5 | 99.6% | 477.93 g/mol | C19H23ClF3N5O2S | 10 MG

Alpelisib hydrochloride is the hydrochloride salt of a selective PI3Kα inhibitor used in research to probe PI3K signaling and PIK3CA-driven oncogenic pathways. Supplied as a high-purity solid in small laboratory pack sizes, it is intended for in vitro and preclinical studies; handle per safety data and institutional protocols.

Selective PI3Kα inhibitor for pathway and cancer research.
High purity (≈99.6%) suitable for analytical and biological assays.
Light yellow to yellow solid physical form.
Available in small research pack sizes, including 10 mg.
Includes core identifiers: CAS number, formula, and molecular weight.
Store sealed at 4°C; in solvent, store at -80°C.

Pricing & Availability

4,166

Medchemexpress LLC Alfuzosin hydrochloride | 81403-68-1 | 99.7% | 5 MG

Alfuzosin hydrochloride (SL 77499-10) is an orally active, selective, and competitive α1-adrenoceptor antagonist. It relaxes the muscles of the prostate and bladder neck, aiding in urination, and can be used in the study of benign prostatic hyperplasia (BPH).

Orally active, selective, and competitive α1-adrenoceptor antagonist.
Relaxes the muscles of the prostate and bladder neck, aiding in urination.
Used in the study of benign prostatic hyperplasia (BPH).

Pricing & Availability

4,167

Medchemexpress LLC Moexipril hydrochloride | 82586-52-5 | 98.4% | 100 MG

Moexipril hydrochloride is an orally active inhibitor of angiotensin-converting enzyme (ACE), and becomes effective by being hydrolyzed to moexiprila (hydrochloride). It exhibits antihypertensive and neuroprotective effects. This compound is for research use only and not sold to patients.

Inhibits angiotensin-converting enzyme (ACE)
Exhibits antihypertensive and neuroprotective effects
Significantly reduces the percentage of damaged neurons
Attenuates Fe2+/3+-induced neurotoxicity
Exhibits dose-dependent and antihypertensive effects in renal hypertensive rats, spontaneously hypertensive rats, and perinephritic hypertensive dogs
Significantly reduces the infarct area on the mouse brain surface
Significantly attenuates the cortical infarct volume in rats

Pricing & Availability

4,168

Medchemexpress LLC 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, hydrochloride (1:1) | 15622-65-8 | 99.8% | 1 ML

Molindone hydrochloride is an orally active and brain-penetrant dopamine D2/D5 receptor antagonist. It exhibits antipsychotic and antidepressant-like activities, suppressing spontaneous locomotion and antagonizing apomorphine-induced emesis. It can be used for research related to neurological diseases.

Orally active and brain-penetrant dopamine D2/D5 receptor antagonist.
Shows antipsychotic and antidepressant-like activities.
Suppresses spontaneous locomotion.
Antagonizes apomorphine-induced emesis.
Can be used for the research of neurological disease.

Pricing & Availability

4,169

Medchemexpress LLC Flavoxate hydrochloride | 3717-88-2 | 99.7% | 500 MG

Flavoxate hydrochloride is an orally active L-type Ca2+ channel inhibitor and antispasmodic. It inhibits cyclic adenosine monophosphate production by blocking voltage-dependent inward Ba2+ currents, regulating the brainstem micturition center, and stimulating G protein-coupled receptors.

Relaxes bladder smooth muscle
Inhibits isovolumetric rhythmic contractions
Increases bladder capacity
Alleviates symptoms of urgent urination frequency and pollakiuria
Suitable for research on overactive bladder and related voiding dysfunctions

Pricing & Availability

4,170

Medchemexpress LLC (R)-Preclamol hydrochloride | 89874-80-6 | 98.0% | 255.78 | 50 MG

(R)-Preclamol hydrochloride ((+)-3-PPP hydrochloride) is the R-enantiomer of Preclamol hydrochloride. It is a DA agonist with autoreceptor as well as postsynaptic receptor stimulatory properties.

Purity of 98.0%
CAS number 89874-80-6
Molecular weight of 255.78
Solid appearance
Off-white to light yellow color
Recommended storage at 4°C, sealed and away from moisture
Soluble in DMSO at 100 mg/mL

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Alcohols and polyols

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Medchemexpress LLC Ssr180711 (hydrochloride) | 446031-79-4 | 99.9% | 361.66 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC EPZ011989 hydrochloride | 2095432-26-9 | 99.4% | 642.27 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ponatinib (hydrochloride) | 1114544-31-8 | 99.8% | 569.02 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ro 41-1049 hydrochloride | 127917-66-2 | MFCD00900596 | 100.0% | 301.77 g·mol⁻¹ | C12H13ClFN3OS | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Zoniporide hydrochloride hydrate | 863406-85-3 | 99.4% | 374.82 g/mol | C17H19ClN6O2 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SGK1-IN-3 hydrochloride | 96.7% | C23H21Cl3N6O3S | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SB-612111 hydrochloride | 99.6% | 454.86 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC ARG1-IN-1 hydrochloride | 00-00-0 | 90.0% | C11H22BClN2O4 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Guanabenz hydrochloride | 23113-43-1 | 99.9% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alpelisib hydrochloride | 1584128-91-5 | 99.6% | 477.93 g/mol | C19H23ClF3N5O2S | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alfuzosin hydrochloride | 81403-68-1 | 99.7% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Moexipril hydrochloride | 82586-52-5 | 98.4% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, hydrochloride (1:1) | 15622-65-8 | 99.8% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Flavoxate hydrochloride | 3717-88-2 | 99.7% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (R)-Preclamol hydrochloride | 89874-80-6 | 98.0% | 255.78 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More