Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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4,156 – 4,170 of 6,662 results

4,156

eMolecules 930-30-3 | 2-Cyclopenten-1-one | Combi-Blocks | MFCD00001401 | 82.102 | C5H6O | 97.000 | O=C1CCC=C1 | 1g | 232308539

2-Cyclopenten-1-one | Combi-Blocks | 930-30-3 | MFCD00001401 | 82.102 | C5H6O | 97.000 | O=C1CCC=C1 | 1g | 232308539

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4,157

Sigma Aldrich Fine Chemicals Biosciences Cholesterol powder, BioReagent, suitable for cell culture, >=99% | 57-88-5 | MFCD00003646 | 25G

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4,158

Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 99.6% | 500 MG

Trazodone hydrochloride is a triazolopyridine derivative classified as a serotonin receptor antagonist and reuptake inhibitor (SARI). It demonstrates anti-depressant and anti-insomnious activity. The compound exerts antagonistic properties against α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects.

Serotonin receptor antagonist and reuptake inhibitor (SARI)
Exhibits anti-depressant and anti-insomnious activities
Antagonizes α1- and α2-adrenergic receptors and histamine H1 receptors
Minimal anticholinergic effects
Binds to 5-HT1A receptor
Reduces expression of neuroinflammatory markers
Increases mRNA expression of BDNF and CREB
Demonstrates neuroprotective effects

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4,159

Medchemexpress LLC Nimustine hydrochloride (ACNU) | 55661-38-6 | 98.2% | 309.15 | 50 MG

Nimustine hydrochloride (ACNU) is the hydrochloride salt form of Nimustine. This alkylating agent induces DNA double-strand breaks (DSBs) and inter-strand crosslinks (ICLs), activating the DNA damage response (DDR) signaling pathway. It also activates the p38 MAPK/JNK signaling pathway and demonstrates antitumor activity.

Exhibits cytotoxicity against human U87MG cells with an IC50 of 0.72 μM.
Activates caspase and AP-1, upregulates bim expression, and promotes c-Jun phosphorylation in LN-229 cells.
Induces apoptosis and increases expressions of cleaved bim and caspase-3/8/9 in LN-229 cells.
Inhibits tumor growth in C3H/HeN mouse models when combined with radiotherapy.

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4,160

Medchemexpress LLC Bleomycin hydrochloride | 67763-87-5 | 99.5% | 100 MG

Bleomycin hydrochloride is a DNA synthesis inhibitor, a DNA damaging agent, and an antitumor antibiotic. It is used for research purposes only. It is considered a radiomimetic compound due to its genetic effects resembling ionizing radiation.

DNA synthesis inhibitor
DNA damaging agent
Antitumor antibiotic
Induces single and double strand breaks and single apurinic/apyrimidinic sites in DNA
Radiomimetic compound
Can be used to create animal models of pulmonary fibrosis

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4,161

Medchemexpress LLC Naluzotan hydrochlo | 5MG

Naluzotan hydrochlo | 5MG

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4,162

Medchemexpress LLC VTP-27999 Hydrochloride | 1264191-73-2 | 98.2% | C26H42Cl2N4O5 | 10MM/1ML

VTP-27999 Hcl is an alkyl amine Renin inhibitor that is useful for Hypertension and End-Organ Diseases. Its IC50 value targets Renin.

Molecular weight: 561.54
Appearance: Solid
Color: White to yellow
Solubility in water: ≥ 100 mg/mL (178.08 mM)
Storage as solid: 4°C, sealed, away from moisture
Storage in solvent: -80°C for 6 months; -20°C for 1 month (sealed, away from moisture)

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4,163

Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 10 MG

Dopexamine hydrochloride | 86484-91-5 | 429.42 | 10 MG

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4,164

Medchemexpress LLC Alpelisib (hydrochloride) | 1584128-91-5 | C19H23ClF3N5O2S | 100 MG

Alpelisib hydrochloride is a potent, orally active, and selective PI3Kα inhibitor with demonstrated antineoplastic activity. It potently inhibits Akt phosphorylation in cells transformed with PI3Kα and also exhibits reduced inhibitory activity in PI3Kβ or PI3Kδ isoforms transformed cells.

Potently inhibits common PIK3CA somatic mutations (H1047R, E545K)
Significantly reduces tumor volumes and ectopic bone matrix deposition in vivo
Induces cell cycle arrest in the G0/G1 phase of human and murine osteosarcoma cell lines
Used in various clinical trials for diverse conditions and phases

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4,165

Medchemexpress LLC Aprindine hydrochloride | 33237-74-0 | 99.0% | 358.95 g·mol⁻¹ | C22H31ClN2 | 10 MG

Aprindine hydrochloride is a class I-b anti-arrhythmic research compound that blocks sodium channels (INa) and is used to study cardiac electrophysiology. Supplied as the hydrochloride salt in small milligram quantities, it is intended for analytical and preclinical research applications.

Class I-b anti-arrhythmic agent; sodium channel blocker.
Hydrochloride salt form for improved solubility.
Available in small, precise milligram pack sizes.
High purity suitable for analytical and preclinical studies.
Used in electrophysiology and cardiovascular research applications.

Pricing & Availability

4,166

Medchemexpress LLC Eperisone (hydrochloride) | 56839-43-1 | 99.95% | 25 MG

Eperisone Hydrochloride is an orally active antispastic agent that also exhibits a vasodilator effect. It is used in research for muscle stiffness and pain. This compound is a potent and selective P2X7 receptor antagonist and also shows antagonism for human P2X3. Eperisone Hydrochloride functions by relaxing both skeletal and vascular smooth muscles, leading to various effects such as reduced myotonia, improved circulation, and suppression of the pain reflex.

Antispastic agent
Vasodilator effect
P2X7 receptor antagonist
P2X3 antagonist
Muscle relaxation
Therapeutic effects
Research use only

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4,167

Medchemexpress LLC PNU 37883 hydrochloride (PNU 37883A) | 57568-80-6 | 99.7% | 381.98 | 50 MG

PNU 37883 hydrochloride (PNU 37883A) is a selective vascular ATP-sensitive potassium (Kir6, KATP) channels blocker. This compound has diuretic effects with specific binding in kidney and vascular smooth muscle rather than in brain or pancreatic beta cells.

Inhibits four types of KATP channels in HEK-293 cells, including Kir6.2/SUR1, Kir6.2/SUR2A, Kir6.2/SUR2B, or Kir6.1/SUR2B.
Inhibits putative smooth muscle KATP channel types, Kir6.2/SUR2B (IC50 of 15 μM) and Kir6.1/SUR2B (IC50 of 6 μM).
Significantly inhibits currents generated by expressing Kir6.2Δ26 alone, with an IC50 of 5 μM, which is increased to 38 μM when expressed with SUR2B.
Produces a concentration-dependent attenuation of the relaxation of agmatine (100 μM) in phenylephrine- or KCl- precontracted aortic rings.
Does not modify vascular tone when used alone at 10 nM.

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4,168

Medchemexpress LLC Alfuzosin (hydrochloride) | 81403-68-1 | 99.7% | 25 MG

Alfuzosin hydrochloride is an orally active, selective, and competitive α1-adrenoceptor antagonist. It relaxes the muscles of the prostate and bladder neck, aiding in urination. This compound is used in the study of benign prostatic hyperplasia (BPH).

Orally active compound
Selective and competitive α1-adrenoceptor antagonist
Relaxes prostate and bladder neck muscles
Aids in urination
Used for benign prostatic hyperplasia (BPH) studies

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4,169

Medchemexpress LLC Alectinib hydrochloride | 1256589-74-8 | 99.9% | 25 MG

Alectinib hydrochloride is a potent, selective, and orally available ALK inhibitor. It demonstrates effective central nervous system (CNS) penetration.

Potent and selective ALK inhibitor
Orally available
Inhibits ALK F1174L and ALK R1275Q
Effective central nervous system (CNS) penetration
Reduces cell activity in a dose-dependent manner
Leads to dose-dependent tumor growth inhibition and regression

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4,170

Medchemexpress LLC Branaplam hydrochloride | 1562338-39-9 | 99.4% | 429.94 | 1 ML

Branaplam (LMI070; NVS-SM1) hydrochloride is a highly potent, selective, and orally active survival motor neuron-2 (SMN2) splicing modulator. It has an EC50 of 20 nM for SMN and inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. This compound is capable of elevating full-length SMN protein and extending survival in a severe spinal muscular atrophy (SMA) mouse model. It is intended for research use only and not for sale to patients.

Highly potent, selective, and orally active SMN2 splicing modulator.
Elevates full-length SMN protein.
Extends survival in a severe spinal muscular atrophy (SMA) mouse model.
Produces dose-dependent elevations of SMN2-FL transcript and SMN protein in brain and spinal cord.
Improves body weight and extends lifespan in n SMN∆7 mice.

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Alcohols and polyols

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Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 99.6% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nimustine hydrochloride (ACNU) | 55661-38-6 | 98.2% | 309.15 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bleomycin hydrochloride | 67763-87-5 | 99.5% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Naluzotan hydrochlo | 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC VTP-27999 Hydrochloride | 1264191-73-2 | 98.2% | C26H42Cl2N4O5 | 10MM/1ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alpelisib (hydrochloride) | 1584128-91-5 | C19H23ClF3N5O2S | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Aprindine hydrochloride | 33237-74-0 | 99.0% | 358.95 g·mol⁻¹ | C22H31ClN2 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Eperisone (hydrochloride) | 56839-43-1 | 99.95% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC PNU 37883 hydrochloride (PNU 37883A) | 57568-80-6 | 99.7% | 381.98 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alfuzosin (hydrochloride) | 81403-68-1 | 99.7% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alectinib hydrochloride | 1256589-74-8 | 99.9% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Branaplam hydrochloride | 1562338-39-9 | 99.4% | 429.94 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More